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Digital transformation, the transition of companies to a remote form of work, the formation of new business models and the development of digitalization over the past few years have established a complex and rapidly changing business environment. The scientific novelty of the article is the modifying role of information security for business. Information security for sustainable business development should be considered as a strategic business unit with a specific innovation program reflected in the corporate development strategy of the company. The study noted that today it is not enough for a business to have software for information security, it is important to consider information security comprehensively with the elaboration of processes, solutions, procedures and the creature of local acts. The conclusions on each factor influencing effective business development are presented. The necessity of improving the regulatory and legal sphere in the field of information security is identified and the rationale for the importance of supporting the implementation of Russian technological solutions along with the increasing role of information security in the company's activities is presented. In the context of digitalization, business information security is the basis for protecting the company's commercial data and maintaining competitiveness in the market. It is proved that the Russian information security market and Russian business are actively and dynamically developing, and the further development of the business depends on its resistance to cyberattacks. It is reasonably proved that business information security in the context of digitalization is the main condition for the success of all commercial activities. The theoretical and practical significance of the study lies in the influence of the consideration of information security factors on the sustainable development of business without reference to the field of activity and it is shown that taking into account these factors is necessary for both small and large businesses. The dynamics of improving regulatory and legal documents in the field of information security is shown, the influence of the normative and terminological apparatus of information security on the development of business solutions in the context of digitalization is revealed.